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Canine Phosphofructokinase (PFK)deficiency Afflicts Springer Spaniels,affecting an Estimated 10% of the Breed.PFK

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Canine phosphofructokinase (PFK) deficiency afflicts springer spaniels,affecting an estimated 10% of the breed.PFK is the glycolytic enzyme that phosphorylates fructose-1-phosphate and catalyzes the committed step in glycolysis.Given its critical role in glycolysis,one implication of the genetic defect resulting in PFK deficiency in dogs is


Definitions:

Lecithin

A fatty substance found in animal and plant tissues, widely used as an emulsifier in food products, cosmetics, and pharmaceuticals.

Triglyceride

A type of fat (lipid) found in your blood, made up of a glycerol backbone attached to three fatty acid chains, the main form of fat stored by the body.

Wax

A diverse class of organic compounds that are malleable at slightly higher than room temperature, consisting mostly of hydrocarbons or esters of fatty acids.

Organic Compound

A chemical compound that contains carbon atoms covalently bonded to hydrogen atoms, possibly along with other elements such as oxygen, nitrogen, sulfur, and halogens.

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