Use the Following Information When Answering the Corresponding Question(s)

question 26

Multiple Choice

Use the following information when answering the corresponding question(s) .
Shu-ichi Nakano reported in Science in February 2000 that "The RNA enzyme (ribozyme) from hepatitis delta virus catalyzes self-cleavage of a ...[chemical] ...bond." This reaction is inherently slow due to the formation of an unfavorable negative charge on the ribozyme.The author goes on to show that this self-cleavage is made faster by joining it with an acid-base reaction that neutralizes the negative charge.Nakano's model describes a positively charged cytosine base on the ribozyme acting as the acid,and magnesium hydroxide acting as the base.Specifically,the cytosine donates its proton (H⁺) to neutralize the unstable negative charge that would have formed on the ribozyme.
-Refer to Nakano's quote from Science.If the cytosine is positively charged (+) before self-cleavage,what would its charge be after self-cleavage?

• A)+ (positive)
• B)- (negative)
• C)0 (neutral)
• D)no way to predict

---

Definitions:

Cost Effective

An approach or method that achieves the desired outcome without excessive expenditure, ensuring optimal use of resources.

Drug Legalization

The process of removing legal prohibitions against drugs, allowing them to be legally produced, sold, and used under regulated conditions.

Material Success

The accumulation of wealth and physical possessions that are often used as a measure of a person's or organization's achievement.

Strain Theory

Holds that people may turn to deviance when they experience strain. Strain results when a culture teaches people the value of material success and society fails to provide enough legitimate opportunities for everyone to succeed.