When Calculating the Recurrence Risk for a Complex, Possibly Polygenic

question 1

Multiple Choice

When calculating the recurrence risk for a complex, possibly polygenic disorder with a couple who already have one child with the disorder, which additional factorhasthe greatest impact on increasing this risk?

• A)The child with the disorder is male, and the overall incidence of the disorder is twice as high in males than females.
• B)Both the mother and the father are heavily exposed to a variety of chemicals in their workplaces.
• C)The father has a nephew with a mild form of the same disorder.
• D)The mother has a brother who also has the same disorder.

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Definitions:

Time Period Assumption

an accounting principle that divides an enterprise's life into small periods of time for reporting and analysis purposes.

Economic Life

The expected period over which an asset remains useful to the owner or until it can generate economic benefits.

Artificial Time Periods

Divisions of time, not naturally occurring, created for the purpose of financial reporting, budgeting, or project scheduling.

Economic Entity Assumption

An accounting principle that treats a company as a separate entity from its owners or shareholders for financial reporting purposes.