How Does Intravenous Enzyme-Replacement Therapy for Gaucher Disease Reduce the Organ

question 23

Multiple Choice

How does intravenous enzyme-replacement therapy for Gaucher disease reduce the organ storage of glucosylceramide?

• A)The enzyme increases the destruction of glucosamine-filled macrophages.
• B)The drug acts as a cofactor, increasing the activity of the mutated enzyme.
• C)The drug increases production of all blood cells in the bone marrow, including white blood cells, which have not stored glucosylceramide.
• D)The enzyme is absorbed through the plasma membranes of affected cells and converts the stored glucosylceramide into its constituent molecules.

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