Karen and Steve Each Have a Sibling with Sickle-Cell Disease

question 48

Short Answer

Karen and Steve each have a sibling with sickle-cell disease. Neither Karen nor Steve nor any of their parents have the disease, and none of them have been tested to reveal sickle-cell trait. Based on this incomplete information, calculate the probability that if this couple has a child, the child will have sickle-cell disease.

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Definitions:

Incidences of Warfare

Occurrences or instances of armed conflict between groups, emphasizing the frequency and distribution of such events over time or space.

Frequent Mobility

The tendency or need to move often, either in short distances within a local area or longer migrations, found in nomadic or certain modern lifestyles.

Chiefdom

A politically organized society in which several neighboring communities inhabiting a territory are united under a single ruler, who is at the head of a ranked hierarchy of people.

Paramount Chief

A supreme leader among a group of chiefs in certain traditional societies, often with political and spiritual authority over a larger area.