Use the Following Information to Answer the Next Few Questions

question 41

Multiple Choice

Use the following information to answer the next few questions.
CML (chronic myelogenous leukemia) results from a translocation between human chromosomes 9 and 22. The resulting chromosome 22 is significantly shorter than usual, and it is known as a Philadelphia (Ph') chromosome. The junction at the site of the translocation causes overexpression of a thymine kinase receptor. A new drug (Gleevec or imatinib) has been found to inhibit the disease if the patient is treated early.
-Why would Gleevec most probably cause remission of the disease?

• A) It reverses the chromosomal translocation.
• B) It eliminates the Ph' chromosome.
• C) It removes Ph'-containing progenitor cells.
• D) The drug inhibits the replication of the affected chromosome.
• E) The drug inhibits the specific thymine kinase receptor.

Analyze the lives of yeoman farmers to distinguish characteristics common in their lifestyle.

Understand the key components and importance of critical thinking.

Apply the principles of critical thinking to assess real-life situations.

Differentiate between strong and weak critical thinking using the Holistic Critical Thinking Scoring Rubric.

---

Definitions:

Conservation

A cognitive ability in child development, identified by Piaget, where a child understands that properties such as mass, volume, and number remain the same despite changes in the forms of objects.

Emotional Attachment

A deep and enduring emotional bond that connects one person to another across time and space.

Primates

An order of mammals that includes humans, apes, monkeys, and prosimians, characterized by large brains, forward-facing eyes, and opposable thumbs.

Telegraphic Speech

A stage in language development where children speak in short, simple phrases, often missing grammatical markers.