Increased Activity of the Neurotransmitter Dopamine at Synapses in the Mesolimbic

question 2

Multiple Choice

Increased activity of the neurotransmitter dopamine at synapses in the mesolimbic dopamine system is known to cause euphoria.Therefore, a good strategy for the development of new euphoriants is to develop drugs that:

• A)Inhibit the sodium cotransporter for dopamine in the nerve terminal.
• B)Inhibit the transporter that pumps dopamine into synaptic vesicles.
• C)Inhibit tyrosine hydroxylase.
• D)Induce enhanced expression of catechol-O-methyltransferase (COMT).
• E)Block voltage-gated calcium channels in the nerve terminals.

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