Hypercholesterolemic Patients Taking 3-Hydroxy-3-Methylglutaryl-Coenzyme a (HMG-CoA) Reductase Inhibitors (Statins) Produce

question 9

Multiple Choice

Hypercholesterolemic patients taking 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) produce less cholesterol from endogenous synthesis.Lower intracellular cholesterol levels induce which of the following regulatory changes?

• A)Enhanced VLDL formation in the liver.
• B)Down-regulation of HMG-CoA reductase.
• C)Higher lipoprotein lipase (LPL) activity.
• D)Higher plasma chylomicron concentration.
• E)An increased number of LDL receptors.

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