In Humans,there Are a Spectrum of Syndromes,including Spondylocostal Dysostosis and Klippel-Feil

question 13

Multiple Choice

In humans,there are a spectrum of syndromes,including spondylocostal dysostosis and Klippel-Feil anomaly,that are characterized by vertebral and rib abnormalities.Genetic mapping studies have identified mutations in several genes that affect one growth factor signaling pathway.Which is the pathway affected?

• A) FGF
• B) BMP
• C) WNT
• D) Retinoic acid
• E) NOTCH

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