The Vertebrae Are Patterned by the Hox Complex of Transcription

question 14

Multiple Choice

The vertebrae are patterned by the Hox complex of transcription factors,which are expressed in nested domains along the cranial-caudal axis.Hox gene expression is regulated by retinoic acid.How would gain of retinoic acid function be expected to affect the developing vertebrae?

• A) Cranialize them.
• B) Caudalize them.

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