The AER,the Thickened Ectoderm at the Distal Tip of the Limb

question 16

Multiple Choice

The AER,the thickened ectoderm at the distal tip of the limb bud,controls limb outgrowth.Genetic inactivation experiments in mice and manipulation studies in chicks have identified the key factors expressed in the AER that control outgrowth once the limb bud has formed.What family of growth factors in the AER promotes outgrowth?

• A) Bmp
• B) Fgfs
• C) Wnts
• D) Shh

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