A 47-Year-Old Woman Had a Mastectomy Because She Had Breast

question 9

Multiple Choice

A 47-year-old woman had a mastectomy because she had breast carcinoma that was previously diagnosed by biopsy.Pathologic examination revealed that several axillary lymph nodes contained metastatic tumors.A test was performed on tumor cells extracted from the mastectomy specimen,which indicated that the tumor cells overexpressed a certain cellular proto-oncogene.On the basis of this test result,the patient was treated with an FDA-approved monoclonal antibody specific for the protein encoded by that gene.Which of the following was most likely the protein target of this antibody therapy?

• A)p53
• B)H-Ras
• C)HPV E7
• D)Rb
• E)Her2

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Definitions:

Coase Theorem

An economic theory that if trade in an externality is possible and there are no transaction costs, bargaining will lead to an efficient allocation of resources regardless of the initial distribution of property rights.

Liability Rules

Legal principles that dictate how responsibilities and damages are to be handled or compensated in cases of harm or infringement.

Bargaining

The process of negotiating the terms of a transaction or agreement between parties, often involving compromises from the initial positions.

Property Rights

The legal rights to possess, use, and dispose of assets including real property, personal property, and intellectual property.