The First Experiments That Demonstrated Protective Adaptive Immune Responses to Tumors

question 8

Multiple Choice

The first experiments that demonstrated protective adaptive immune responses to tumors involved transplantation of chemical carcinogen-induced tumors between rodents.Which of the following facts was learned from these experiments?

• A)There are only a limited number of antigens that can evoke a protective anti-tumor response.
• B)Transplanted sarcomas can evoke protective cytolytic T lymphocyte responses.
• C)Carcinomas express tumor antigens that are recognized by T lymphocytes.
• D)Protective immune responses against tumors are largely mediated by antibodies.
• E)Spontaneously arising tumors are often eradicated by cytolytic T lymphocytes.

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