In Reference to Detecting Minimal Residual Disease, Which of the Following

question 15

Multiple Choice

In reference to detecting minimal residual disease, which of the following is true?

• A)PCR, karyotyping and Southern blot analysis are equally sensitive and specific.
• B)PCR is most sensitive for detecting low levels of tumor burden.
• C)Karyotyping is capable of detecting 0.1% tumor burden.
• D)Southern Blot analysis has 100% sensitivity and specificity for detecting aberrant proteins formed as a result of the genetic mutation.

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