-In a Disease Associated with a Nucleotide Repeat,anticipation Is Often

question 17

Multiple Choice

-In a disease associated with a nucleotide repeat,anticipation is often noticed in subsequent generations,usually associated with a more severe phenotype.Which of the following is a more likely cause of anticipation?

• A)There is more frequent unequal crossing over.
• B)Subtle phenotypic nuances are more often sought by a physician.
• C)Family members are exposed to the same mutagens.
• D)Highly repeated sequences are expressed more often.
• E)The sequences have greater stability in later generations.