How Does the Philadelphia Chromosome Activate an Oncogene

question 2

Multiple Choice

How does the Philadelphia chromosome activate an oncogene?

• A) It puts a proto-oncogene downstream of a strong promoter
• B) It fuses a proto-oncogene with another protein and alters its activity
• C) It deletes its opposing tumor suppressor
• D) It deletes a regulatory region for the gene
• E) It removes its 3' UTR

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