How Might Antisense Oligonucleotides Be Used to Alleviate the Severity

question 1

Multiple Choice

How might antisense oligonucleotides be used to alleviate the severity of Duchenne muscular dystrophy?

• A) By causing the degradation of mutant transcripts
• B) By upregulating the expression of the mutant gene
• C) By blocking the transcription of the mutant gene
• D) By replacing the mutant sequence
• E) By blocking exon splice enhancers so that the exon containing the mutation is skipped

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Definitions:

Machismo

A cultural attitude or behavior marked by exaggerated masculinity and often associated with dominance over women and children.

Conduct Disorders

Behavioral and emotional disorders in children and adolescents characterized by long-term patterns of rule-violating behavior.

Family Income

The combined total income earned by all members of a household, which is used to determine the household's economic status.

Native American

Pertaining to the indigenous peoples of the United States, including American Indians and Alaska Natives.