Selective Estrogen Receptor Modulators (SERMs) Are Known to Inhibit Bone

question 2

Multiple Choice

Selective estrogen receptor modulators (SERMs) are known to inhibit bone resorption and prevent fractures. Their mechanism of action is:

• A) Decrease production of interleukins that up regulate osteoclasts
• B) Promote follicular production of progesterone, prostaglandin F₂α, and proteolytic enzymes
• C) Suppress the hypothalamic-pituitary axis
• D) Decrease plasma calcium levels
• E) Increase activity of the hypothalamic GnRH pulse generator

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