In an Experiment, Mutation of Bases at the Very 5

question 27

Multiple Choice

In an experiment, mutation of bases at the very 5' end of the togavirus genome reduces the amount of the negative-strand of the genome produced.What does this result suggest?

• A) That the virus genome contains an IRES sequence.
• B) That the packaging sequence is only found at the 5' end of the genome.
• C) That the replication complex binds to both ends of the genome.
• D) That the genome forms a covalently closed circle for replication.
• E) That a protein is used as a primer for genome replication.

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