Release of Succinate from Succinyl-CoA Can Be Coupled to GTP

question 20

Multiple Choice

Release of succinate from succinyl-CoA can be coupled to GTP synthesis because:

• A) The amide bond between succinate and CoA has a large -DG of hydrolysis.
• B) The thioester bond between succinate and CoA has a large -DG of hydrolysis.
• C) The link between succinate and CoA involves an acid anhydride to phosphate.
• D) Coenzyme A is a "high energy" compound, just like GTP.
• E) None of these explains why GTP can be formed during this reaction.

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