Which Is True for Using Mass Spectroscopy as a Chromatography

question 20

Multiple Choice

Which is true for using mass spectroscopy as a chromatography detector?
I Selected ion monitoring observes only one to four m/z to create a selected ion chromatogram.
II Extracted ion chromatogram records the entire mass spectrum for the compounds coming off the column,picking one m/z from the collected mass spectra to create the chromatogram.
III Reconstructed total ion chromatogram records the total ion current below a certain m/z to generate the chromatogram.
IV Selected reaction monitoring creates a chromatogram using a triple quadrupole mass spectrometer.Quadrupole 1 selects the precursor ion.In quadrupole 2,the precursor ion is fragmented through collisions with N₂ or Ar gas.All fragment ions pass to quadrupole 3,which selects one ion fragment to monitor.

• A)I,II,III,and IV
• B)II,III,and IV
• C)I and IV
• D)IV only
• E)I,II,and IV

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Definitions:

Exclusionary

Pertaining to the act or policy of excluding certain people or groups from participating in an activity, institution, or society.

Clinical Research

The in-depth examination of an individual or a group by a clinician who assists with psychological or medical problems.

Ethnocentric Bias

The tendency to view one's own culture or ethnicity as superior and to use one’s own cultural standards to judge others.

Biased Sample

A sample that does not accurately represent the population from which it was drawn due to systematic exclusion or over-representation of certain groups.