Which Is True for Using Mass Spectroscopy as a Chromatography

question 20

Multiple Choice

Which is true for using mass spectroscopy as a chromatography detector?
I Selected ion monitoring observes only one to four m/z to create a selected ion chromatogram.
II Extracted ion chromatogram records the entire mass spectrum for the compounds coming off the column,picking one m/z from the collected mass spectra to create the chromatogram.
III Reconstructed total ion chromatogram records the total ion current below a certain m/z to generate the chromatogram.
IV Selected reaction monitoring creates a chromatogram using a triple quadrupole mass spectrometer.Quadrupole 1 selects the precursor ion.In quadrupole 2,the precursor ion is fragmented through collisions with N₂ or Ar gas.All fragment ions pass to quadrupole 3,which selects one ion fragment to monitor.

• A)I,II,III,and IV
• B)II,III,and IV
• C)I and IV
• D)IV only
• E)I,II,and IV

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