In Yeast,U2 SnRNA Base-Pairs to a Short Sequence near Branch-Point

question 27

Essay

In yeast,U2 snRNA base-pairs to a short sequence near branch-point A in introns.In higher eukaryotes,this branch-point sequence is not highly conserved,and a protein called U2AF promotes binding of U2 snRNA to pre-mRNA.You have produced mice with a knockout mutation in the U2AF gene.Would you expect mice heterozygous for the U2AF knockout mutation to be viable? Would you expect mice homozygous for the U2AF knockout mutation to be viable?

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Definitions:

Cow's milk

A common dairy product obtained from the milk of cows, used as a beverage or food ingredient.

Solid foods

Foods that are not liquid or pureed, introduced to an infant’s diet typically around six months of age to complement breastmilk or formula.

Whole cow's milk

The complete, unaltered milk obtained from cows, rich in nutrients like fat, protein, vitamins, and minerals, generally consumed after infancy.

Months old

A measure of age, particularly used for infants and young children, indicating the number of months since birth.