Using a Luciferase Reporter System in Tissue Culture Cells,researchers from the University

question 43

Essay

Using a luciferase reporter system in tissue culture cells,researchers from the University of California,San Francisco,found that ethanol stimulates transcription of genes in brain cells possibly involved in the adaptive responses to alcohol.This process was found to depend on PKA activation.By analogy to other PKA-dependent transcription activation pathways,describe a possible pathway for this transcription induction.What other proteins would be involved?

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