How Is Hemoglobin S (HbS)formed in Sickle Cell Disease

question 51

Multiple Choice

How is hemoglobin S (HbS) formed in sickle cell disease?

• A) By a deficiency in glucose 6-phosphate dehydrogenase (G-6-PD)that changes hemoglobin A to hemoglobin S
• B) By a genetic mutation in which two amino acids (histidine and leucine)are missing
• C) By a genetic mutation in which one amino acid (valine)is replaced by another (glutamic acid)
• D) By an autoimmune response in which one amino acid (proline)is detected as an antigen by abnormal immunoglobulin G (IgG)

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