Transgenic Mice Engineered to Contain the Mutant Versions of the Huntingtin

question 56

Short Answer

Transgenic mice engineered to contain the mutant versions of the huntingtin gene with various numbers of _____________________ repeats have phenotypes similar to humans affected by Huntington disease.

---

Definitions:

Phospholipid Bilayer

A critical component of all cell membranes, consisting of two layers of phospholipids which provide barriers and pathways for substances entering or exiting the cell.

Integral Protein

A type of membrane protein that is permanently attached to the biological membrane, playing critical roles in transport and signal transduction.

Chromosomes Condense

The process by which chromosomes become shorter and thicker, making them visible under a microscope, typically occurring during cell division.

Spindle Fibers

Filaments formed during cell division that help segregate chromosomes into the daughter cells.