Which of the Following Is Correct Concerning the Dissociation Constant

question 35

Multiple Choice

Which of the following is correct concerning the dissociation constant, K_d, of a drug X?

• A) A larger K_d implies tighter target to drug binding.
• B) The K_d corresponds to the concentration of drug that binds to 90% of the target.
• C) The K_d can be determined from the simple saturation curve of a binding reaction.
• D) The apparent K_d increases as the K_M of the true substrate increases.
• E) None of the answers is correct.

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