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You Are Working at a Biotechnology Company That Specializes in the Scale-Up

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Essay

You are working at a biotechnology company that specializes in the scale-up and purification of enzymes derived from bacterial sources for human therapeutics.One of your responsibilities is to ensure that the 180-liter industrial fermenter in the pilot plant does not exceed 37°C during the batch synthesis phase.Explain why attention to this particular detail is important.


Definitions:

Annual Holding Cost

The total expenses associated with storing unsold goods or materials for a year, including warehousing, insurance, depreciation, and obsolescence costs.

UPS

United Parcel Service, a global parcel delivery and supply chain management company.

Cross Dock Distribution Center

A logistics strategy where incoming shipments are unloaded, sorted, and directly loaded onto outbound trucks, minimizing storage time.

Milk Runs

A logistics term for a round trip that facilitates either distribution or collection, aiming to maximize efficiency and reduce transportation costs.

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