Select the Primary Reason Why the Use of Ketamine (Ketolar)

question 5

Multiple Choice

Select the primary reason why the use of ketamine (Ketolar) would be contraindicated in patients with a history of hypertension.

• A) Ketamine stimulates the sympathetic nervous system, so blood pressure and heart rate may be elevated during the anesthesia.
• B) Ketamine competitively inhibits the activity at the benzodiazepine recognition site on the GABA receptor, leading to elevated blood pressure and heart rate.
• C) Ketamine activates the alpha₂ adrenergic receptors in the CNS and inhibits sympathetic activity, resulting in increased blood pressure and heart rate.
• D) None of these are correct.

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Definitions:

Norepinephrine

A neurotransmitter and hormone involved in arousal and stress, mood regulation, and blood pressure maintenance.

Temperamentally Inhibited

A trait characterized by a tendency to react with fear or withdrawal in new situations or environments.

Amygdala

An almond-shaped, temporal lobe structure that plays a central role in emotion and evaluating stimuli.

Interaction Between Person

Involves communication and exchange of ideas, feelings, or behaviors between two or more individuals.