In the Mechanism of Chymotrypsin, Which of the Following Amino

question 1

Multiple Choice

In the mechanism of chymotrypsin, which of the following amino acids found in the active site is correctly defined in terms of its role in the reaction?

• A)serine: hydrogen bonds with carbonyl oxygen to withdraw electron density from the substrate
• B)histidine: deprotonates aspartic acid to allow a nucleophilic attack to occur
• C)aspartic acid: electrostatic stabilization of histidine to make a stronger base
• D)cysteine: performs a nucleophilic attack on the carbonyl carbon of the substrate
• E)none of the above

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