In Bacteria, the Biosynthetic Routes for Proline and Arginine Diverge $\delta$

question 9

Multiple Choice

In bacteria, the biosynthetic routes for proline and arginine diverge when glutamate is N-acetylated for arginine synthesis. Which of the following explains why acetylation is required for arginine synthesis but not proline synthesis?

• A)acetylation alters the pK_a of the amine group
• B)acetylation prevents reduction of the amine group in N-acetylglutamate- \(\delta\)-semialdehyde
• C)acetylation activates the amine group for synthesis of the guanidine group of arginine
• D)acetylation prevents the cyclization of N-acetylglutamate-\(\delta\)-semialdehyde
• E)none of the above

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