The Fact That the Following Molecule Serves as a Substrate

question 25

Multiple Choice

The fact that the following molecule serves as a substrate for DNA polymerase in place of dTTP proves what issue with regard to DNA replication?

• A)DNA polymerase is highly error prone
• B)hydrogen bonding to N-3 of thymine is not critical for substrate recognition
• C)base stacking is the true driving force for nucleotide placement
• D)substrate shape might be as important as hydrogen bonding for DNA polymerase
• E)none of the above

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