Which of the Following Is True Regarding the RB Gene

question 12

Multiple Choice

Which of the following is true regarding the RB gene in relation to cancer and the cell cycle?
1) In many types of cancer both copies of the RB gene have been inactivated.
2) Inactivation of both copies of the RB gene impair the ability of the RB protein to bind E2F transcription factors.
3) pRB is phosphorylated through the action of cyclin-dependent kinases.

• A) 1
• B) 2
• C) 3
• D) 1 and 2
• E) All of these

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Definitions:

Writ of Certiorari

An order issued by a higher court to a lower court to transfer the records of a specific case for review.

Administrative Law

The rules and regulations governing the function and powers of the executive branch of government.

Judicial Review

Power held by the courts to review decisions made by administrative decision makers.

Statement of Claim

A legal document filed in court outlining the plaintiff's claims against the defendant and the basis for those claims.