An Adaptive Walk of Beta-Lactamase in Response to Selective Pressure

question 54

Multiple Choice

An adaptive walk of beta-lactamase in response to selective pressure exerted by cefotaxime likely involved:

• A)the random generation of five changes that provide microbial resistance to the antibiotic.
• B)sequential changes in single amino acids that each provided an incremental level of resistance to the antibiotic.
• C)increased genetic change induced by selective pressure exerted by the antibiotic.
• D)one clear beneficial change and several non-impactful changes in the gene.
• E)major shifts in the metabolic pathways in the microbe under selection.

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