Considering the Same Unidentified Proteins Discussed in the Question 32

question 3

Multiple Choice

Considering the same unidentified proteins discussed in the question 32 above (UPS-1 through UPS-3) what can you conclude from the following observations and the knowledge you gained in this chapter?
OBSERVATIONS:
1) UPS-1 is capable of autophosphorylation.
2) UPS-2 becomes phosphorylated only when UPS-1 is phosphorylated.
3) UPS-2,when phosphorylated interacts with UPS-3 and activates the Ras protein.
4) Recombinant UPS-2 protein that has a mutation resulting in the replacement of tyrosine for serine in the binding region loses all function.
5) The proteins Jun and Fos are expressed at high levels in the presence of UPS-1,2,3.

• A)The UPS signaling system functions as a heterotrimeric G protein signaling cascade.
• B)Sugarish appears to solicit a similar insulin response to that expected from glucose.
• C)Sugarish must be sensitive to the phosphoinositide pathway.
• D)Calmodulin (CaM)would likely alter the activity of the UPS proteins.
• E)None of the above are possible conclusions.

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