The So-Called "First Generation" of Antidepressants

question 137

Multiple Choice

The so-called "first generation" of antidepressants:

• A)include the tricyclics and MAO inhibitors and affect multiple neurotransmitter pathways in the brain.
• B)include Prozac, Zoloft, and Paxil and affect only serotonin in the brain.
• C)have very few side effects.
• D)have limited effectiveness and were used primarily in combination with electroconvulsive therapy.

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Definitions:

Ocular Dominance Columns

Stripes of neurons in the visual cortex of the brain that process signals from one eye more than the other.

On-Center Cells

Neurons that respond with an increase in firing rates when light falls on the center of their receptive field and decrease when light falls on the surrounding areas of the field.

Off-Center Cells

Neurons, particularly in the retina, that respond to a decrease in light intensity in their center with increased activity, playing a critical role in visual contrast detection.

Blob Regions

Areas in the visual cortex characterized by their high metabolic activity and involvement in the processing of color and visual information.