In a Complement-Dependent Cytotoxicity Assay, Lymphocytes Were Incubated in the Presence

question 13

Multiple Choice

In a complement-dependent cytotoxicity assay, lymphocytes were incubated in the presence of antibody of known HLA specificity. Complement was added, and the cells absorbed trypan blue. What is the interpretation of this assay?

• A) The lymphocytes express antigens specific for the antibodies in the assay.
• B) The lymphocytes do not have antigens specific for the antibodies in the assay.
• C) This is not a valid method for identifying HLA antigens.
• D) The cells are resistant to complement lysis.

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Definitions:

Natural Monopoly

A situation in the market where due to high initial costs and substantial economies of scale, a single firm can supply a product or service at a lower cost than any potential competitor, leading to a market dominated by one supplier.

Network Effects

Increases in the value of a product to each user, including existing users, as the total number of users rises.

Rent-seeking Behavior

Activities undertaken by individuals or firms to increase their own wealth without creating new wealth, often through manipulating the social or political environment in which economic activities occur.

X-inefficiency

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