Which Event Would Lead to a Reduction in Gene Expression

question 116

Multiple Choice

Which event would lead to a reduction in gene expression?

• A) Mutation of the DNA-binding domain of an activator, changing its shape
• B) Mutation of the binding site of a co-repressor molecule within a repressor protein
• C) Removal of all methylation marks from a region of DNA
• D) Remodeling of the chromatin environment, resulting in removal of histone octamers from a gene's promoter region
• E) Mutation of a TATA box to create a tighter binding of RNA polymerase to the DNA

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