Refer to the Figure Showing the Steps Used in Microarray

question 102

Essay

Refer to the figure showing the steps used in microarray analysis to detect differences in expression between tumor tissue and normal tissue.The spots in the bottom panel represent individual genes for patients who have good prognoses (left) as well as for patients who have poor ones (right).The colors of those spots represent levels of expression: red = high expression, yellow = intermediate expression, green = low expression. Look at the lowest, right-most gene in both patterns.Does expression of this gene correlate with the prognoses? Explain your answer.

---

Definitions:

Ultrapure Dimethylamine

A highly purified form of dimethylamine, which is an organic compound used in the synthesis of a wide range of chemicals.

Proton Spectrum

The range of frequencies or energies that protons exhibit in nuclear magnetic resonance (NMR) spectroscopy, revealing molecular structure.

Carbon-Carbon Splitting

A chemical process that involves breaking the bond between two carbon atoms in a compound.

DEPT-90

A nuclear magnetic resonance (NMR) spectroscopy technique that distinguishes between CH and CH3 groups in a molecule by phase modulation.