Refer to the Figure

question 125

Multiple Choice

Refer to the figure. Members of the JAK family of nonreceptor kinases are involved in signaling pathways.The four paralogs JAK1, JAK2, JAK3, and TYK2 are found in humans, mice, chickens, and fish, as shown in the phylogenetic tree.According to this phylogenetic gene tree,

• A) fruit fly hopscotch is more closely related to human TYK2 than human JAK1.
• B) a duplication event led to the generation of the orthologs human JAK3 and mouse Jak3.
• C) two duplication events in common ancestors to fish and humans created the orthologs JAK1, JAK2, JAK3, and TYK2.
• D) both jak2a orthologs are pseudogenes.
• E) JAK2 and JAK3 are examples of convergent evolution.

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Definitions:

Negotiates

The process of discussing and reaching a mutual agreement between parties, often involving the terms and conditions of a contract.

Delivery

The act of transporting goods from one location to another.

HDC Status

Stands for "Holder in Due Course" status, a legal term indicating a party has acquired a negotiable instrument in good faith and without notice of any defect.

Good Faith

The honest intent to act without taking an unfair advantage over another party, characterized by honesty and fairness in dealings.