A Client Has Been Started on Diltiazem (Cardizem),a Susbstrate of the Cytochrome

question 1

Multiple Choice

A client has been started on diltiazem (Cardizem) ,a susbstrate of the cytochrome CYP3A4 isoenzyme system.The client also takes phenobarbital,an inducer of the CYP3A4 isoenzyme system,for seizures.What does the nurse recognize about diltiazem?

• A)It will not be able to cross the blood brain barrier (BBB).
• B)It will be metabolized by the kidneys.
• C)It might be inactivated at a faster rate than normal.
• D)It might be excreted at a slower rate.

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Definitions:

Purchase Consideration

The total value transferred by an acquirer to purchase another company, including cash, securities, and other assets or liabilities undertaken.

NCI

Non-Controlling Interest, which represents the portion of equity in a subsidiary not owned by the parent company, showing the equity interest of minority shareholders.

Shareholders

Individuals or entities that own shares in a corporation, thereby having ownership in and potential financial claim on its assets and earnings.

Consolidation Working Papers

Documents used in preparing consolidated financial statements, detailing the adjustments and eliminations made.