Potentially Fatal Granulocytopenia Has Been Associated with Treatment of Hyperthyroidism

question 22

Multiple Choice

Potentially fatal granulocytopenia has been associated with treatment of hyperthyroidism with propylthiouracil. Patients should be taught to report:

• A) Tinnitus and decreased salivation
• B) Fever and sore throat
• C) Hypocalcemia and osteoporosis
• D) Laryngeal edema and difficulty swallowing

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Definitions:

Citric Acid Cycle

A series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate.

Acetyl CoA

A molecule that conveys the carbon atoms within the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized for energy production.

NADH

NADH stands for Nicotinamide Adenine Dinucleotide (Hydrogen), a coenzyme found in all living cells that plays a fundamental role in producing energy through the process of oxidation-reduction.

Oxidized

A chemical reaction in which a substance loses electrons, often leading to the gain of oxygen or loss of hydrogen, affecting the substance's charge and reactivity.