Which S_N2 Reaction Will Occur Most Rapidly in Aqueous Acetone $\rightarrow$

question 99

Multiple Choice

Which S_N2 reaction will occur most rapidly in aqueous acetone solution? Assume concentrations and temperature are the same in each instance.

• A) HO^- + CH₃-Cl \(\rightarrow\) CH₃OH + Cl^-
• B) HO^- + CH₃CH₂-Cl \(\rightarrow\)CH₃CH₂OH + Cl^-
• C) HO^- + (CH₃)₂CH-Cl \(\rightarrow\)(CH₃)₂CHOH + Cl^-
• D) HO^- + (CH₃)₃C-Cl \(\rightarrow\)(CH₃)₃COH + Cl^-
• E) HO^- + (CH₃)₃CCH₂-Cl \(\rightarrow\)(CH₃)₃CCH₂OH + Cl^-

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Definitions:

Two-sided Test

A statistical hypothesis test which determines if there is a significant difference in either direction between the groups or variables being studied.

One-sided Test

A hypothesis test in which the alternative hypothesis specifies a direction of the statistical significance, either greater than or less than a certain value.

P-value

The probability of encountering test data at least as extreme as what has been observed, with the assumption that the null hypothesis is valid.

Two-sided Test

A hypothesis test in which the critical area of a distribution is two-sided and tests whether a sample is either greater than or less than a certain range of values.