The Nucleosome Is the Basic Repeating Unit of Chromatin

question 2

Multiple Choice

The nucleosome is the basic repeating unit of chromatin. Which of the following statements concerning nucleosomes is incorrect:

• A) nucleosomes have protein cores consisting of an octamer of protein subunits
• B) a segment of DNA approximately 145 bp long is associated with each nucleosome
• C) histone H1 contacts the DNA linker segments as they enter and leave the nucleosome
• D) the DNA in a nucleosome is packed tightly inside the protein core to conserve space in the nucleus and to protect the DNA from damage
• E) some nucleosomes form over specific regions of DNA in a non_random manner

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