If the Non-Hydrolyzable ATP Analog β,γ-Methylene-ATP Were Given to Muscle

question 30

Multiple Choice

If the non-hydrolyzable ATP analog β,γ-methylene-ATP were given to muscle cells, where would inhibition occur?

• A) during formation of the cross bridge between actin and myosin when Pi is released
• B) during the conformational change in the myosin head that moves actin and myosin relative to each other
• C) during the ATP binding step where actin and myosin dissociate
• D) during the conformational change in the myosin head when ATP hydrolysis occurs
• E) at steps c and d above

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