Which of the Following Are Relevant to the Reaction Catalyzed

question 14

Multiple Choice

Which of the following are relevant to the reaction catalyzed by chorismate mutase?

• A) the reaction involves a concerted intramolecular rearrangement of chorismate to prephenate during the synthesis of phenylalanine.
• B) the enzyme catalyzed and uncatalyzed reactions follow almost identical routes
• C) the enzymatic reaction is thought to involve transition state stabilization by 12 electrostatic and hydrogen bond interactions
• D) the geometry of the enzyme active site is such that the difference in energy between ES and the near attack conformation is less than 1 kJ/mol
• E) all of the above are true

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