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What Amino Acid Is Made to Replace Another Amino Acid α\alpha

question 113

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What amino acid is made to replace another amino acid in membrane-spanning α\alpha -helices by site-directed mutagenesis of the gene coding for the protein? This is done in order to determine how close together two such α\alpha -helices are in the structure of an integral protein.The amino acid is added to facilitate the formation of crosslinks between α\alpha -helices that are in close proximity.


Definitions:

Annually Compounded

A compound interest calculation where the interest is added to the principal at the end of each year.

Nominal Rate

The stated interest rate of a bond or loan, without accounting for compounding or inflation.

Mortgage Loan

A loan secured by real property through the use of a mortgage note which evidences the existence of the loan and the encumbrance of that realty.

Compounded Monthly

A method where the interest is calculated on a monthly basis and added to the principal sum, allowing the interest to grow over time through compounding.

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