CAR T Cells Have Shown Remarkable Efficacy in Treating Hematological

question 9

Multiple Choice

CAR T cells have shown remarkable efficacy in treating hematological malignancies . Figure Q17) In this cartoon, the component of the CAR indicated by the arrow is composed of:

• A) A T-cell receptor specific for mesothelin
• B) The ligand that normally binds to mesothelin
• C) The Fab fragment of an anti-mesothelin antibody
• D) A co-stimulatory receptor signaling domain
• E) The CD3 signaling components of the T-cell receptor

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Definitions:

Visual Angle

A measure of the size an object appears to an observer, determined by the object's actual size and its distance from the observer.

Figure-ground

A perceptual phenomenon where the focus is on a central object (figure) while the rest (ground) forms a background, showcasing how our perception separates visual stimuli.

Monocular Cue

A visual signal that allows for depth perception and estimation of an object's distance using just one eye.

Superposition

A principle in physics that for any two overlapping waves, the resulting wave is obtained by adding the amplitudes of the individual waves at each point.