10) a Mouse Model for Autoimmune Hemolytic Anemia Can Be

question 28

Multiple Choice

10) A mouse model for autoimmune hemolytic anemia can be transferred to naive mice by a single injection of anti-red blood cell IgG antibodies. However, the disease is prevented if recipient mice lack IgG-binding Fc receptors. These data indicate:

• A) An essential role for NK cells, neutrophils and other granulocytes, and macrophages in red blood cell destruction
• B) An essential role for the transport of IgG out of the blood into the tissues for red blood cell destruction
• C) A critical role for innate immune cells in the development of autoreactive antibody-secreting B cells
• D) That phagocytosis of antibody-coated red blood cells is only mechanism leading to red blood cell destruction
• E) Autoantibodies can traffic to the bone marrow and destroy erythroid progenitor cells

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Definitions:

Reflex

An automatic, involuntary response to a specific stimulus, typically serving as a protective mechanism.

Unethical

Actions or behaviors that violate moral, professional, or societal standards, often causing harm or disadvantage to others.

UCS

Unconditioned Stimulus; a stimulus that naturally triggers a response without prior conditioning in the context of classical conditioning.

Operant Conditioning

A learning process where the consequences of a behavior affect the likelihood of that behavior occurring again.