Genetic Variations in Proteins Involved in Immune and Inflammatory Responses

question 25

Multiple Choice

Genetic variations in proteins involved in immune and inflammatory responses have been shown to be associated with the development of atopic dermatitis and other allergic diseases. However, several genes associated with these conditions do not affect the immune system directly. For example, among this latter group are genes that:

• A) Regulate the recruitment of inflammatory cells to the airways or other mucosa
• B) Function in cytokine receptor signaling pathways
• C) Encode proteins expressed in airway epithelial cells
• D) Regulate barrier function by airway and skin epithelial cells
• E) Are common to atopic diseases and to autoimmune diseases

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Definitions:

Correlation

A statistical measure that indicates the extent to which two or more variables fluctuate together.

Engine Size

A measure of the volume of the combustion chambers in a vehicle's engine, typically expressed in liters or cubic centimeters, often linked to the power output.

Gas Mileage

The distance a vehicle can travel per unit volume of fuel, usually measured in miles per gallon (mpg) or kilometers per liter (km/l).

Scatterplot

A graphical representation of data using Cartesian coordinates to display values for two variables for a set of data, revealing any correlations between them.